Can metabolomic profiling predict response to therapy?

Can we predict the response to cyclosporine?

P71: Which Variables Predict the Response of Patients with Social Anxiety Disorder to Cognitive-Behavior Therapy?

Social anxiety (or social phobia) disorder is defined as a constant fear of being embarrassed or negatively evaluated in social situations or while doing activities in the presence of others. Several studies have examined the role of certain variables that might predict response to treatment and may affect treatment outcome. The purpose of this study was to identify predictive variables of chan...

Metabolomic profiling predicts outcome of rituximab therapy in rheumatoid arthritis

OBJECTIVE To determine whether characterisation of patients' metabolic profiles, utilising nuclear magnetic resonance (NMR) and mass spectrometry (MS), could predict response to rituximab therapy. 23 patients with active, seropositive rheumatoid arthritis (RA) on concomitant methotrexate were treated with rituximab. Patients were grouped into responders and non-responders according to the Ameri...

CT scans predict response to cancer therapy.

Metabolomic Profiling to Identify Predictors of Response to Vitamin E for Non-Alcoholic Steatohepatitis (NASH)

Vitamin E was recently shown to improve hepatic histology in a randomized controlled trial of pioglitazone or vitamin E for nonalcoholic steatohepatitis (PIVENS). The current study utilized samples collected in the PIVENS trial to identify: (1) baseline metabolomic profiles that could identify who would respond to vitamin E treatment and (2) end of treatment metabolomic profiles reflective of h...